Development is a process whereby a relatively unspecified system comprised of loosely connected lower level parts becomes organized into a coherent, higher-level agency. Its temporal corollaries are growth, increasingly deterministic behavior, and a progressive reduction of developmental potential. During immature stages with relatively low specification and high potential, development is largely controlled by local interactions from the “bottom-up,” whereas during more highly specified stages with reduced potential, emergent autocatalytic processes exert “top-down” control. Robert Ulanowicz has shown that this phenomenology of (...) ascendency follows thermodynamic principles and can be described quantitatively using information theory, providing a general theory of development. However, the theory has not found a wide audience among developmental biologists, as genetic determinism encourages the popular reductionistic perception that ontogeny is controlled entirely by molecular mechanisms that exert efficient causality from the bottom-up. Nonetheless, measurements of metabolic rates and mRNA complexity in developing embryos, as well as functional analyses of gene regulatory systems, indicate that ontogeny fits the paradigm of developmental ascendency. Beyond informing biomedical research and the interpretation of large datasets obtained by systems-biological approaches, developmental ascendency helps explain the origin of life, and, being independent of scale, provides an overarching explanation for phylogenetic change that contextualizes Darwinian evolution. (shrink)

800x600 In our book _Global Insanity_ we argued that the existential predicament faced by humanity is a predictable consequence of Western Enlightenment thinking and the resulting world model, whose ascendance with the Industrial Revolution entrained development of the global consumer Economy that is destroying the biosphere. This situation extends from a dominant mindset based on the philosophy of reductionism. The problem was recognized and characterized by Robert M. Hutchins. In 1985, Hutchins ideas were discussed by Robert Rosen in Chapter 1 (...) of _Anticipatory Systems: Philosophical, Mathematical & Methodological Foundations_._ _Building on Hutchins' ideas, Rosen laid the foundation for an entire new, non-reductionist paradigm, which he called "complexity theory". This new paradigm is what we are further developing here. One has to recognize that a paradigm shift is needed to overcome the entrenched mindset and world model that reductionism has created. Here we explore the myriad interconnected ways-psychological, social, cultural, political, and technological-that the Western world model and consumer economy works as a complex system to thwart, neutralize, or co-opt for its own ends any effort to bring about the kind of radical change that is needed to avert global ecological catastrophe and societal collapse. This resistance to change stems from the need, inherent in the Western model, to continually grow the consumer economy. The media's continued portrayal of consumptive economic growth as a good thing, the widely held belief that the Economy is paramount, and current political and technological trends all manifest the system's active resistance to change. From the perspective of the mature economic system, any work that does not serve to grow the Economy is counterproductive, and viewed as unnecessary, a luxury, or subversive. The potential for real change is thus inversely related to the viability of the Economy, which will eventually decline as the system develops into senescence. To the extent that the fragile metastability of senescence affords opportunity for radical change, economic decline can be viewed as a hopeful sign. But taking maximum advantage of that opportunity will be extraordinarily difficult, as it will require widespread recognition of the problem, major voluntary sacrifice by the relatively large numbers of people who still benefit from the system, and concerted "grassroots" efforts. It can be expected that the system will resist those efforts until the end, becoming increasingly reliant on media-enabled distraction and divisive politics, as well as violent coercion, to maintain itself. Investment in education and science is widely touted as necessary for improving our situation, but this is misguided as long as the educational system and scientific enterprise continue to work in collusion with the larger system, as they currently do. Until the reductionist mindset and world model that drives the system is effectively challenged, there can be little hope for the kind of change needed to avert the catastrophic collapse of civilization. Normal 0 false false false EN-AU X-NONE X-NONE MicrosoftInternetExplorer4. (shrink)

Chance has somewhat different meanings in different contexts, and can be taken to be either ontological or epistemological . Here I argue that, whether or not it stems from physical indeterminacy, chance is a fundamental biological reality that is meaningless outside the context of knowledge. To say that something happened by chance means that it did not happen by design. This of course is a cornerstone of Darwin’s theory of evolution: random undirected variation is the creative wellspring upon which natural (...) selection acts to sculpt the functional form of organisms. In his essay Chance & Necessity, Jacques Monod argued that an intellectually honest commitment to objectivity requires that we accord chance a central role in an otherwise mechanistic biology, and suggested that doing so may well place the origin of life outside the realm of scientific tractability. While that may be true, ongoing research on the origin of life problem suggests that a biogenesis may have been possible, and perhaps even probable, under the conditions that existed on primordial earth. Following others, I argue that the world should be viewed as causally open, i.e. primordially indeterminate or vague. Accordingly, chance ought to be the default scientific explanation for origination, a universal ‘null hypothesis’ to be assumed until disproven. In this framework, creation of anything new manifests freedom , and causation manifests constraint, the developmental emergence of which establishes the space of possibilities that may by chance be realized. (shrink)